Detection of a z=0.0515, 0.0522 absorption system in the QSO S4 0248+430 due to an intervening galaxy

In some of the few cases where the line of sight to a Quasi-Stellar Object (QSO) passes near a galaxy, the galaxy redshift is almost identical to an absorption redshift in the spectrum of the QSO. Although these relatively low redshift QSO-galaxy pairs may not be typical of the majority of the narrow heavy-element QSO absorption systems, they provide a direct measure of column densities in the outer parts of galaxies and some limits on the relative abundances of the gas. Observations are presented here of the QSO S4 0248+430 and a nearby anonymous galaxy (Kuhr 1977). The 14 second separation of the line of sight to the QSO (z sub e = 1.316) and the z=0.052 spiral galaxy, (a projected separation of 20 kpc ((h sub o = 50, q sub o = 0)), makes this a particularly suitable pair for probing the extent and content of gas in the galaxy. Low resolution (6A full width half maximum), long slit charge coupled device (CCD) spectra show strong CA II H and K lines in absorption at the redshift of the galaxy (Junkkarinen 1987). Higher resolution spectra showing both Ca II H and K and Na I D1 and D2 in absorption and direct images are reported here

“She was a disgrace to her sex” : Prostitution and Moral Panic in London, Ontario, 1880-1885

This thesis examines the lives and work of prostitutes in London, Ontario, from 1880 to 1885. The city’s sex trade was shaped by class, and women worked in upscale houses of ill-fame, disorderly houses, or on the streets. Prostitutes performed domestic and sexual labour in the same spaces, and their daughters often entered the sex trade, creating a multi-generational profession. In addition to class, a woman’s race and age shaped her experience in sex work and ability to protect her labour interests from local authorities. Sex workers increasingly became the target of repressive reform efforts from the city’s elites. Late-nineteenth century London witnessed a moral panic about vice. Believing that their ways of life were under threat from women who did not conform to Victorian standards of morality, they demonized prostitutes. Despite their victimization and abuse, women of various backgrounds responded to their oppression with resilience

The destructive influence of the past: A neglected theme in the novels of Jules Barbey d'Aurevilly

After setting Barhey d'Aurevilly in his literary context, then discussing the research that has been carried out on various aspects of his work, with reference to his waxing and waning popularity as a writer, the thesis will demonstrate that in the novels of Barbey d'Aurevilly, the personal past of the character - that is, some major emotional upheaval in his past - acts as a powerful destructive force which ruins the character's chance of present and future happiness, as well as that of those around him. As Barbey progresses as a writer, this theme will be developed and enriched without being altered in any essential way; the earlier novels show the protagonists experiencing some passionate affair in their past which in the present renders them incapable of reciprocating the feelings of love they arouse in others and in turn, they "infect" these others with their own inability to love (Ce qui ne meurt pas - L'Amour impossible - Une Vielle Maitresse). In the later novels, this idea is widened to include other passions: pride in L'Ensorcelee and in Un Pretre marie; excessive patriotism in Le Chevalier des Touches, and the past, in the first novels a psychological burden within the characters, will develop into a malefic influence, with the underlying theme of fatality and this combination will lead to tragedy in the later novels. Barbey's own attitude to the past is illustrated by reference to his letters and diaries; he sees' 'the past as a necessary part of his artistic talent and in his later letters especially, admits the powerful influence that his own past has had on him. Ties of friendship, for example, seem to have an almost sacred importance to Barbey. This is the positive side of the past for him, but he also sees it as something we can never be rid of, using words such as "chaine" and "esclavage" to describe it. Memories are seen as a cause of deep pain, those which go furthest back being the most painful. His own unhappy love affair with his cousin's wife Louise marked both his fictional and non-fictional writings. There is an interesting parallel between Barbey's novels and his private writings. Those letters written at the same time as Ce qui ne meurt pas show the sane preoccupation with the personal past as does the novel; but when Barbey became involved with Madame de Bouglon in the early 1850, he deliberately denied the influence of the past in his letters and diaries of the period, in an obvious attempt to please her; however, at the same time, the theme of the destructive past in his novels becomes more complex and psychologically richer. The impression is of Barbey consciously suppressing something that was vital to him, so much so that it inevitably emerged in his fictional writings. All Barbey's novels express the same theme: upbringing and an emotional upheaval in the past of his characters invariably ruins their present happiness and that of those close to them. This reflected a deep preoccupation in Barbey d'Aurevilly himself, a preoccupation with the past, closely linked to his conception of his own literary talents

Incontinence-specific quality of life measures used in trials of treatments for female urinary incontinence: a systematic review.

This systematic review examined the use of incontinence-specific QOL measures in clinical trials of female incontinence treatments, and systematically evaluated their quality using a standard checklist. Of 61 trials included in the review, 58 (95.1%) used an incontinence-specific QOL measure. The most commonly used were IIQ (19 papers), I-QoL (12 papers) and UDI (9 papers). Eleven papers (18.0%) used measures which were not referenced or were developed specifically for the study. The eight QOL measures identified had good clinical face validity and measurement properties. We advise researchers to evaluate carefully the needs of their specific study, and select the QOL measure that is most appropriate in terms of validity, utility and relevance, and discourage the development of new measures. Until better evidence is available on the validity and comparability of measures, we recommend that researchers consider using IIQ or I-QOL with or without UDI in trials of incontinence treatments

Distinct amino acid compositional requirements for formation and maintenance of the [PSI+] prion in yeast

Multiple yeast prions have been identified that result from the structural conversion of proteins into a self-propagating amyloid form. Amyloid-based prion activity in yeast requires a series of discrete steps. First, the prion protein must form an amyloid nucleus that can recruit and structurally convert additional soluble proteins. Subsequently, maintenance of the prion during cell division requires fragmentation of these aggregates to create new heritable propagons. For the Saccharomyces cerevisiae prion protein Sup35, these different activities are encoded by different regions of the Sup35 prion domain. An N-terminal glutamine/asparagine-rich nucleation domain is required for nucleation and fiber growth, while an adjacent oligopeptide repeat domain is largely dispensable for prion nucleation and fiber growth but is required for chaperone-dependent prion maintenance. Although prion activity of glutamine/asparagine-rich proteins is predominantly determined by amino acid composition, the nucleation and oligopeptide repeat domains of Sup35 have distinct compositional requirements. Here, we quantitatively define these compositional requirements in vivo. We show that aromatic residues strongly promote both prion formation and chaperone-dependent prion maintenance. In contrast, nonaromatic hydrophobic residues strongly promote prion formation but inhibit prion propagation. These results provide insight into why some aggregation-prone proteins are unable to propagate as prions

Taking Control of What Counts in Accountability: The Context Enriched Report Card

During the last two decades concerns about the quality of education have resulted in widespread calls for educational improvement and reform in many nations

The Pragmatist in Context of a National Science Foundation Supported Grant Program Evaluation: Guidelines and Paradigms

Background:  The philosophical underpinnings of evaluation guidelines set forth by a funding agency can sometimes seem inconsistent with that of the intervention. Purpose: Our purpose is to introduce questions pertaining to the contrast between the instructional program’s underlying philosophical beliefs and assumptions and those underlying our evaluation approach. Drawing heavily on Scriven, we discuss these from a pragmatist evaluation stance in light of issues defined by Lincoln and Guba (2000). The discussion is couched in the evaluation of an innovative approach to teaching computer science. Setting: Auburn University, Auburn, AL Intervention: The evaluation is designed to investigate the effects of a studio-based teaching approach in computer science education. The evaluation framework employs a rigorous design that seeks to provide evidence to support or refute some assumed truth about the object (or construct) investigated. The program evaluated is steeped in a constructivist framework which assumes that no universal truth or reality exists, but rather, is constructed by the individual. Research Design: Our evaluation design, to a good extent, reflects a post-positivist, quasi-experimental position. We also include a qualitative component using student interviews. Data Collection and Analysis: Evidence of the effectiveness of the instructional approach for learning is assessed quantitatively using pre- and post-test and pre- and post-survey data group comparisons (mixed design ANOVA). Interviews provide the basis for qualitative theme analysis. Findings: Quantitative results were somewhat weak but consistent in support of the studio-based teaching. Interview data suggest that most students did find working in groups enjoyable and a valuable experience

Computers in the EFL Writing Class : Hindrance or Help?

最近では、英語の授業において広くコンピューターが使われるようになってきている。しかし、従来の教育手法とは異なり、コンピューターを利用するには、語学学習には関係のないスキルが求められる。本論の目的は、大学レベルの英作文のクラスで用いられるコンピューターが効果的な道具として機能して学習プロセスを利しているか、それとも逆にその妨げとなっているのかを調査することである。二つの異なるサーベイ結果は、調査対象者がMSワードなどの文書作成プログラムを使いこなすために必要なスキルを習得しているのみならず、彼らが英作文をする際、紙に直接書くよりもコンピューターを使うことを好んでいることを示した

Developing educational competencies for dissemination and implementation research training programs: An exploratory analysis using card sorts

Abstract Background With demand increasing for dissemination and implementation (D&I) training programs in the USA and other countries, more structured, competency-based, and tested curricula are needed to guide training programs. There are many benefits to the use of competencies in practice-based education such as the establishment of rigorous standards as well as providing an additional metrics for development and growth. As the first aim of a D&I training grant, an exploratory study was conducted to establish a new set of D&I competencies to guide training in D&I research. Methods Based upon existing D&I training literature, the leadership team compiled an initial list of competencies. The research team then engaged 16 additional colleagues in the area of D&I science to provide suggestions to the initial list. The competency list was then additionally narrowed to 43 unique competencies following feedback elicited from these D&I researchers. Three hundred additional D&I researchers were then invited via email to complete a card sort in which the list of competencies were sorted into three categories of experience levels. Participants had previous first-hand experience with D&I or knowledge translation training programs in the past. Participants reported their self-identified D&I expertise level as well as the country in which their home institution is located. A mean score was calculated for each competency based on their experience level categorization. From these mean scores, beginner-, intermediate-, and advanced-level tertiles were created for the competencies. Results The card sort request achieved a 41 % response rate (n = 124). The list of 43 competencies was organized into four broad domains and sorted based on their experience level score. Eleven competencies were classified into the “Beginner” category, 27 into “Intermediate,” and 5 into “Advanced.” Conclusions Education and training developers can use this competency list to formalize future trainings in D&I research, create more evidence-informed curricula, and enable overall capacity building and accompanying metrics in the field of D&I training and research.http://deepblue.lib.umich.edu/bitstream/2027.42/113065/1/13012_2015_Article_304.pd